Menù principale
B016997 - CLINICAL MORPHOPHYSIOLOGY
Main information
Teaching Language
Course Content
Suggested readings
Learning Objectives
Prerequisites
Teaching Methods
Further information
Type of Assessment
Course program
Sustainable Development Goals 2030
Academic Year 2022-23
Course year
First year - First Semester
Belonging Department
Biomedical, Experimental and Clinical Sciences "Mario Serio"
Course Type
Single education field course
Scientific Area
BIO/09 - PHYSIOLOGY
Credits
6
Teaching Hours
48
Teaching Term
26/09/2022 ⇒ 13/01/2023
Attendance required
No
Type of Evaluation
Final Grade
Course Content
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Course program
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Lectureship
Teaching Language
Italian
Course Content
The course requires the knowledge of macroscopic morphology, relations, and microscopic organization, physiology and biophysics concerning the organs of the systems: circulatory (heart), urinary (kidney) as well as macroscopic and microscopic morphology of endocrine system. Knowledge include notions of pharmacological and pathological aspects of each topic to the aim of developing a clinical overall view.
Suggested readings (Search our library's catalogue)
Fisiologia - D’Angelo-Peres, Edi.Ermes; Fisiologia Umana - Fondamenti, Edi.Ermes
Learning Objectives
The acquisition of an appropriate background of exemplifying cell, tissue, organs & system functions aim to develop the scientific and clinical attitude of students to be extended to every apparatus of human body. The understanding of the integration of physiological functions, which characterize the performance of the human body in health, will be used as a starting base to understand pathological alterations as well as the principles of drug action and the strategies of regenerative medicine.
Prerequisites
Propedeuticity
Teaching Methods
Lectures
Further information
Materiale didattico e programma del corso disponibile su Moodle UNIFI.
Type of Assessment
The final exam consists of a written examination composed of open and multiple choice questions. The exam consists of 3 parts that can be taken at different times: A) Morphology (multiple choice questions; 30 min duration); B) cardiac electrophysiology and pharmacology (open and multiple choice questions; 40 min duration); C) Physiology and pharmacology of cardiovascular and renal systems (open and (multiple choice questions; 30 min duration) The exam aims to
ascertain: i) the acquisition of knowledge relating to the topics
of anatomy, physiology and pharmacology present in the program
ii) the ability to
fully express the issues addressed, through
the use of an appropriate scientific language; iii) the ability to
argue the answers critically, demonstrating the ability correlate the different program topics. The
examination will consist in 2-3 questions ascertaining the achievement of the training objectives prefixed by each different part of the program.
.
The teaching modules will include
separate examination sessions and the final grade
will be the weighted average of the evaluations obtained in the various modules, taking into account their different weight.
ascertain: i) the acquisition of knowledge relating to the topics
of anatomy, physiology and pharmacology present in the program
ii) the ability to
fully express the issues addressed, through
the use of an appropriate scientific language; iii) the ability to
argue the answers critically, demonstrating the ability correlate the different program topics. The
examination will consist in 2-3 questions ascertaining the achievement of the training objectives prefixed by each different part of the program.
.
The teaching modules will include
separate examination sessions and the final grade
will be the weighted average of the evaluations obtained in the various modules, taking into account their different weight.
Course program
1. Urinary Apparatus
Morfology. General organization – kidney, renal calix and pelvis – renal circulation – the nephron.
Fisiologia. Renal function - fluid and electrolyte balance. Glomerular filtration rate and its control. Tubular function. ADH and Aldosterone. Countercurrent multiplication mechanism. Homeostatic functions (osmolarity, volume, pH and systemic pressure control). Clearance.
Pharmacology. Drugs acting on renal function: diuretics, renin–angiotensin–aldosterone system drugs, non steroidal anti inflamamtory drugs.
Nephrology . Renal pathologies- cellular and molecular basis.
2. Cardiovascular apparatus
Morfology: General organization. Heart and conduction system
Physiology: Cardiac action potential in the working myocardium and conduction system: principal currents and channels associated to cardiac action potential and pacemaker potential. Excitation-contraction coupling. Contractility and cardiac cycle. Cardiac ejection and its regulation. Regulation of cardiac function. Smooth muscle and regulation of blood flow in microcirculation. Short term regulation of blood pressure.
Pharmacology : Antiarrhythmic drugs - beta-blockers - cardiac glycosides.
Cardiology: Common cardiac pathologies- atherosclerosis - coronary acute syndrome – heart failure- cardiac ischemia- hypertrophic cardiomyopathy. Diagnostic tools and traditional and innovative treatments.
Morfology. General organization – kidney, renal calix and pelvis – renal circulation – the nephron.
Fisiologia. Renal function - fluid and electrolyte balance. Glomerular filtration rate and its control. Tubular function. ADH and Aldosterone. Countercurrent multiplication mechanism. Homeostatic functions (osmolarity, volume, pH and systemic pressure control). Clearance.
Pharmacology. Drugs acting on renal function: diuretics, renin–angiotensin–aldosterone system drugs, non steroidal anti inflamamtory drugs.
Nephrology . Renal pathologies- cellular and molecular basis.
2. Cardiovascular apparatus
Morfology: General organization. Heart and conduction system
Physiology: Cardiac action potential in the working myocardium and conduction system: principal currents and channels associated to cardiac action potential and pacemaker potential. Excitation-contraction coupling. Contractility and cardiac cycle. Cardiac ejection and its regulation. Regulation of cardiac function. Smooth muscle and regulation of blood flow in microcirculation. Short term regulation of blood pressure.
Pharmacology : Antiarrhythmic drugs - beta-blockers - cardiac glycosides.
Cardiology: Common cardiac pathologies- atherosclerosis - coronary acute syndrome – heart failure- cardiac ischemia- hypertrophic cardiomyopathy. Diagnostic tools and traditional and innovative treatments.
Sustainable Development Goals 2030
3
15
15