Menù principale
B029483 - DIAGNOSTICS OF MALE INFERTILITY AND CRIOCONSERVATION OF MALE GAMETES
Main information
Teaching Language
Course Content
Suggested readings
Learning Objectives
Prerequisites
Teaching Methods
Further information
Type of Assessment
Course program
Sustainable Development Goals 2030
Academic Year 2021-22
Course year
Second year - First Semester
Belonging Department
Biomedical, Experimental and Clinical Sciences "Mario Serio"
Course Type
Single education field course
Scientific Area
MED/13 - ENDOCRINOLOGY AND METABOLISM
Credits
3
Teaching Hours
24
Teaching Term
27/09/2021 ⇒ 15/01/2022
Attendance required
No
Type of Evaluation
Final Grade
Course Content
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Course program
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Lectureship
Teaching Language
italian
Course Content
Suggested readings (Search our library's catalogue)
1. Tournaye H, Krausz C, Oates RD. Novel concepts in the aetiology of
male reproductive impairment. Lancet Diabetes Endocrinol. 2016 Jul 6.
pii: S2213-8587(16)30040-7. 2: Tournaye H, Krausz C, Oates RD.
Concepts in diagnosis and therapy for male reproductive impairment.
Lancet Diabetes Endocrinol. 2016 Jul 6. pii: S2213-8587(16)30043-2. doi:
10.1016/S2213-8587(16)30043-2. 3: Krausz C, Escamilla AR, Chianese C.
Genetics of male infertility: from research to clinic. Reproduction. 2015
Nov;150(5):R159-74. doi: 10.1530/REP-15-0261. Review. 4: Krausz C.
Male infertility: pathogenesis and clinical diagnosis. Best Pract Res Clin
E n d o c r i n o l M e t a b . 2 0 1 1 A p r ; 2 5 ( 2 ) : 2 7 1 - 8 5 . d o i :
10.1016/j.beem.2010.08.006. Review. 5. EAA/EMQN Guidelines
(disponibile online) Krausz et al (2014) EAA/EMQN best practice
guidelines for molecular diagnosis of Y-chromosomal microdeletions:
state-of-the-art 2013; Andrology, 2014, 2, 5–19;
male reproductive impairment. Lancet Diabetes Endocrinol. 2016 Jul 6.
pii: S2213-8587(16)30040-7. 2: Tournaye H, Krausz C, Oates RD.
Concepts in diagnosis and therapy for male reproductive impairment.
Lancet Diabetes Endocrinol. 2016 Jul 6. pii: S2213-8587(16)30043-2. doi:
10.1016/S2213-8587(16)30043-2. 3: Krausz C, Escamilla AR, Chianese C.
Genetics of male infertility: from research to clinic. Reproduction. 2015
Nov;150(5):R159-74. doi: 10.1530/REP-15-0261. Review. 4: Krausz C.
Male infertility: pathogenesis and clinical diagnosis. Best Pract Res Clin
E n d o c r i n o l M e t a b . 2 0 1 1 A p r ; 2 5 ( 2 ) : 2 7 1 - 8 5 . d o i :
10.1016/j.beem.2010.08.006. Review. 5. EAA/EMQN Guidelines
(disponibile online) Krausz et al (2014) EAA/EMQN best practice
guidelines for molecular diagnosis of Y-chromosomal microdeletions:
state-of-the-art 2013; Andrology, 2014, 2, 5–19;
Learning Objectives
to obtain basic knowledge about diagnostic techniques used in male infertility and for sperm cryconservation; to acquire knowledge in bioinformatics in order to be able to interprete genetic data (NGS). To acquire knowledge about molecular genetic methods
Prerequisites
Teaching Methods
frontal lessons and practical part in groups
Further information
contact directly Prof Krausz by email: csilla.krausz@unifi.it
Type of Assessment
oral exam
Course program
Frontal classes: Etiopathogenesis of male infertility and genetics of male
infertility Hormonal regulation of spermatogenesis, hormone dosage
(technical aspects and clinical meaning) Y chromoosme-linked
microdeletion analysis Practical part: the basis of bioinformatics and of
molecular genetics -Techniques of sperm cryoconservation
infertility Hormonal regulation of spermatogenesis, hormone dosage
(technical aspects and clinical meaning) Y chromoosme-linked
microdeletion analysis Practical part: the basis of bioinformatics and of
molecular genetics -Techniques of sperm cryoconservation