Menù principale
B014253 - PHARMACOLOGY I
Main information
Teaching Language
Course Content
Suggested readings
Learning Objectives
Prerequisites
Teaching Methods
Further information
Type of Assessment
Course program
Academic Year 2017-18
Coorte 2014 - 6-years Single Cycle Degree in Medicine and Surgery
Course year
Fourth year - Second Semester
Belonging Department
Experimantal and Clinical Medicine
Modulo di sola Frequenza of
Scientific Area
BIO/14 - PHARMACOLOGY
Credits
4
Teaching Hours
48
Teaching Term
26/02/2018 ⇒ 30/04/2019
Attendance required
Yes
Type of Evaluation
Giudizio Finale
Course Content
show
Course program
show
Lectureship
- Part A MANNAIONI GUIDO
- Part A MUGELLI ALESSANDRO
- Part A VANNACCI ALFREDO
- Part B CERBAI ELISABETTA
- Part B MASINI EMANUELA
- Part C CHIARUGI ALBERTO
- Part C GEPPETTI PIERANGELO
Teaching Language - Part A
Italian
Teaching Language - Part B
Italiano o inglese
Course Content - Part A
Major objective of the course is to provide the pharmacological basis of therapeutics, including toxicology and drug addiction. Medicines representative of therapeutic classes are illustrated for their chemical nature, pharmacological action(s), mechanism(s) of action, therapeutic indication(s), pharmacokinetic characteristics, efficacy, safety, adverse reactions, toxicity, contraindications, drug interactions, doses and administration route.
Course Content - Part B
The first part describes the development and policy of drugs in the context of the Italian and European health system, including regulatory aspects. The second describes pharmacokinetics and pharmacodynamics; receptors and drugs for the main transmitters and autacoids (autonomic nervous system, histamine, serotonin). The last part describes drugs for diseases affecting the respiratory, gastrointestinal and urogenital apparatus, the endocrine system, and for inflammatory and autoimmune diseases.
Suggested readings - Part A (Search our library's catalogue)
GOODMAN & GILMAN's. The pharmacological basis of therapy; 13th ed, 2017
ROSSI F, CUOMO V, RICCARDI C. -Farmacologia. Principi di base e applicazioni Terapeutiche, Edizioni Minerva Medica 2017
KATZUNG & TREVOR A.J. -Basic and Clinical Pharmacology, 14th Ed , Lange , 2017
ROSSI F, CUOMO V, RICCARDI C. -Farmacologia. Principi di base e applicazioni Terapeutiche, Edizioni Minerva Medica 2017
KATZUNG & TREVOR A.J. -Basic and Clinical Pharmacology, 14th Ed , Lange , 2017
Suggested readings - Part B (Search our library's catalogue)
GOODMAN L.S. & GILMAN A.: The pharmacological basis of therapeutics 12th or 13th ed.
Learning Objectives - Part A
Formative assessment: Knowledge and understanding: pharmacological bases for the treatment of human diseases including the effects of abuse and toxic substances. Ability to apply knowledge and understanding: representative drugs of the various therapeutic classes (chemical nature, pharmacological actions, mechanism of action, therapeutic indications, pharmacokinetic, efficacy, safety, adverse effects, toxicity, contraindications, interactions with other drugs, doses and routes of administration).
Learning Objectives - Part B
Pharmacological basis of drug effects and principles of pharmacotherapy, including adverse and toxic effects, drug interactions, controindications.
Prerequisites - Part A
/
Prerequisites - Part B
All exams of the 3rd year are strongly recommnded, in particular physiology, general pathology, semeiotics, microbiology.
Teaching Methods - Part A
/
Teaching Methods - Part B
Lectures and on-line slides and articles
Further information - Part A
/
Further information - Part B
3rd year, second semester
Type of Assessment - Part A
/
Type of Assessment - Part B
Starting 2016-2017, the student will be requested to pass a pre-assessment (multiple choice test) on general pharmacology. A positive evaluation will be mandatory to be admitted to the oral examination on special pharmacology and toxicology (4th year of course).
Course program - Part A
/
Course program - Part B
GENERAL PHARMACOLOGY
1. Drug development: role of pharmaceutical companies, national health and political system, regulatory agencies, public and private research and development organizations.
2. Pharmacokinetics.
3. Pharmacodynamics: drug-receptor interactions and signalling pathways, agonists/antagonists, dose effect relationship
4. Adverse drug reactions and interactions; beneficial/risk effect
5. Pharmacology of sympathetic and parasympathetic systems
6. Pharmacology of ion channels; local anaesthetics
SPECIAL PHARMACOLOGY (part 1)
1. Pharmacology of serotonin and dopaminergic system; antiemetics
2. Histamine system; anti-H1 drugs
3. Pharmacology of gastrointestinal function
4. Anti-inflammatory drugs and immunomodulation (NSAIDS, corticosteroids, immuno-suppressants and –stimulants); pharmacotherapy of gout and rheumatic arthritis .
5. Pulmonary pharmacology
6. Hormones and hormone antagonists (thyroid function, bone turnover, estrogens and progestins)
7. Drugs for urogenital tract (bladder motility and erectile dysfunction)
8. Ocular pharmacology
1. Drug development: role of pharmaceutical companies, national health and political system, regulatory agencies, public and private research and development organizations.
2. Pharmacokinetics.
3. Pharmacodynamics: drug-receptor interactions and signalling pathways, agonists/antagonists, dose effect relationship
4. Adverse drug reactions and interactions; beneficial/risk effect
5. Pharmacology of sympathetic and parasympathetic systems
6. Pharmacology of ion channels; local anaesthetics
SPECIAL PHARMACOLOGY (part 1)
1. Pharmacology of serotonin and dopaminergic system; antiemetics
2. Histamine system; anti-H1 drugs
3. Pharmacology of gastrointestinal function
4. Anti-inflammatory drugs and immunomodulation (NSAIDS, corticosteroids, immuno-suppressants and –stimulants); pharmacotherapy of gout and rheumatic arthritis .
5. Pulmonary pharmacology
6. Hormones and hormone antagonists (thyroid function, bone turnover, estrogens and progestins)
7. Drugs for urogenital tract (bladder motility and erectile dysfunction)
8. Ocular pharmacology