Menù principale
B016913 - CLINICAL BIOCHEMISTRY AND CLINICAL PATHOLOGY
Main information
Teaching Language
Course Content
Suggested readings
Learning Objectives
Prerequisites
Teaching Methods
Type of Assessment
Course program
Sustainable Development Goals 2030
Academic Year 2023-24
Course year
Third year - First Semester
Belonging Department
Experimantal and Clinical Medicine
Course Type
Single education field course
Scientific Area
MED/05 - CLINICAL PATHOLOGY
Credits
6
Teaching Hours
48
Teaching Term
18/09/2023 ⇒ 22/12/2023
Attendance required
No
Type of Evaluation
Final Grade
Course Content
show
Course program
show
Lectureship
Teaching Language
ITALIAN
Course Content
CLINICAL PATHOLOGY
blood count, urine and stool analysis, erythrocyte sedimentation rate. POCT. Diabetes diagnosis. Autoimmunity. Haemostasis. Liver and kidney function. Metabolic diseases. Thyroid. Trace elements. Pharmacogenetics and pharmacogenomics. Genetic pathology: hereditary diseases of connective tissue.
CLINICAL BIOCHEMISTRY: Plasma proteins: definition, causes of alteration in human physiology and pathology, assay methods.
Clinical enzymology: main alterations and assay methods.
blood count, urine and stool analysis, erythrocyte sedimentation rate. POCT. Diabetes diagnosis. Autoimmunity. Haemostasis. Liver and kidney function. Metabolic diseases. Thyroid. Trace elements. Pharmacogenetics and pharmacogenomics. Genetic pathology: hereditary diseases of connective tissue.
CLINICAL BIOCHEMISTRY: Plasma proteins: definition, causes of alteration in human physiology and pathology, assay methods.
Clinical enzymology: main alterations and assay methods.
Suggested readings (Search our library's catalogue)
CLINICAL PATHOLOGY
-Antonozzi-Gullotta,
Medicina di Laboratorio –
Piccin 2014, seconda edizione
CLINICAL BIOCHEMISTRY
- Ciaccio-Lippi,
Biochimica clinica e medicina di laboratorio.
Edises-2017.
-Antonozzi-Gullotta,
Medicina di Laboratorio –
Piccin 2014, seconda edizione
CLINICAL BIOCHEMISTRY
- Ciaccio-Lippi,
Biochimica clinica e medicina di laboratorio.
Edises-2017.
Learning Objectives
CLINICAL PATHOLOGY
Objectives of this teaching are: to know and know how to interpret the first level analyses in order to move towards a correct clinical diagnosis. Learn the advantages and disadvantages of the analyzes performed at the patient's bed and the equipment used. To know the various types of mutations in man, their mechanisms and effects on proteins. To learn how to perform a genotype-clinical or biochemical phenotype correlation using the inherited pathologies of connective tissue as a model. To learn the interaction between genetic variability and pharmacological therapies, the importance of trace elements and a proper metabolism of amino acids in our body.
CLINICAL BIOCHEMISTRY
Learning of the clinical relevance of the main laboratory parameters dealing with tissue and organ damage.
Objectives of this teaching are: to know and know how to interpret the first level analyses in order to move towards a correct clinical diagnosis. Learn the advantages and disadvantages of the analyzes performed at the patient's bed and the equipment used. To know the various types of mutations in man, their mechanisms and effects on proteins. To learn how to perform a genotype-clinical or biochemical phenotype correlation using the inherited pathologies of connective tissue as a model. To learn the interaction between genetic variability and pharmacological therapies, the importance of trace elements and a proper metabolism of amino acids in our body.
CLINICAL BIOCHEMISTRY
Learning of the clinical relevance of the main laboratory parameters dealing with tissue and organ damage.
Prerequisites
CLINICAL PATHOLOGY
Propedeuticity approved by degree cours
CLINICAL BIOCHEMISTRY
General concepts of biochemistry, genetics and biology
Propedeuticity approved by degree course
Main concepts of general biochemistry and metabolism.
Propedeuticity approved by degree cours
CLINICAL BIOCHEMISTRY
General concepts of biochemistry, genetics and biology
Propedeuticity approved by degree course
Main concepts of general biochemistry and metabolism.
Teaching Methods
CLINICAL PATHOLOGY frontal lessons and professional formative activities CLINICAL BIOCHEMISTRY
frontal lessons and professional formative activities
During the COVID period the lessons will be delivered in part in frontal, in video and in video and voice recording at the same time or only in video and video and voice recording at the same time
frontal lessons and professional formative activities
During the COVID period the lessons will be delivered in part in frontal, in video and in video and voice recording at the same time or only in video and video and voice recording at the same time
Type of Assessment
CLINICAL PATHOLOGY
Oral examination
Oral examination
Course program
CLINICAL PATHOLOGY
The Clinical Pathology deals with: a) first level analysis to direct the patient towards a correct clinical diagnosis: urinalysis (characteristics of functional tests and main tests used in the clinic: measurement of glomerular filtrate, creatinine and urea, examination of urine: preanalytic and analytical variability, sensitivity and specificity) and renal pathologies (nephritic and nephrotic syndromes, renal failure, proteinuria, hematology); hepatic and metabolic disorders (amino aciduria); stool analysis and gastrointestinal diseases (hemorrhoids, rhagades, ulcers, esophagitis, gastritis, tumors), blood tests and anemia (classification of the test and the parameters that compose it, physiological variability, application to the diagnosis of the main pathological hematological pictures with particular attention to the diagnosis of anemia), inflammatory states, autoimmune diseases, endocrine diseases, hemostasis disorders, internal organs, oligoelements dosing. Innovative techniques in the field of laboratory medicine and rare diseases in the clinical-laboratory field. Decentralized analyzes (Point of Care Testing): general principles; main methods of study in hemostasis and clinical chemistry. Principle of the method and implementation. Clinical meaning and interpretation of the result.
Glucose metabolism and diabetes. Blood sugar and diabetes: study methods, their clinical significance and interpretation. Therapeutic drug monitoring. Pharmacogenetics and pharmacogenomicsGenetic-clinical pathology: types of mutations in humans, interpretation of the results of mutational analyzes applied to the model of inherited pathologies of connective tissue.
CLINICAL BIOCHEMISTRY
Quality control in laboratory medicine.Plasmatic proteins assessment and alterations. Protein electrophoresis. Clinical enzymology. Main organ/tissue function and damage markers.Laboratory test for glucose homestasis and non protein azo compounds.
The Clinical Pathology deals with: a) first level analysis to direct the patient towards a correct clinical diagnosis: urinalysis (characteristics of functional tests and main tests used in the clinic: measurement of glomerular filtrate, creatinine and urea, examination of urine: preanalytic and analytical variability, sensitivity and specificity) and renal pathologies (nephritic and nephrotic syndromes, renal failure, proteinuria, hematology); hepatic and metabolic disorders (amino aciduria); stool analysis and gastrointestinal diseases (hemorrhoids, rhagades, ulcers, esophagitis, gastritis, tumors), blood tests and anemia (classification of the test and the parameters that compose it, physiological variability, application to the diagnosis of the main pathological hematological pictures with particular attention to the diagnosis of anemia), inflammatory states, autoimmune diseases, endocrine diseases, hemostasis disorders, internal organs, oligoelements dosing. Innovative techniques in the field of laboratory medicine and rare diseases in the clinical-laboratory field. Decentralized analyzes (Point of Care Testing): general principles; main methods of study in hemostasis and clinical chemistry. Principle of the method and implementation. Clinical meaning and interpretation of the result.
Glucose metabolism and diabetes. Blood sugar and diabetes: study methods, their clinical significance and interpretation. Therapeutic drug monitoring. Pharmacogenetics and pharmacogenomicsGenetic-clinical pathology: types of mutations in humans, interpretation of the results of mutational analyzes applied to the model of inherited pathologies of connective tissue.
CLINICAL BIOCHEMISTRY
Quality control in laboratory medicine.Plasmatic proteins assessment and alterations. Protein electrophoresis. Clinical enzymology. Main organ/tissue function and damage markers.Laboratory test for glucose homestasis and non protein azo compounds.