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B030987 - BIOCHEMISTRY
Main information
Teaching Language
Course Content
Suggested readings
Learning Objectives
Teaching Methods
Type of Assessment
Course program
Academic Year 2020-21
Coorte 2020 - 3-years First Cycle Degree (DM 270/04) in MIDWIFERY
Course year
First year - First Semester
Belonging Department
Experimantal and Clinical Medicine
Modulo di sola Frequenza of
Scientific Area
BIO/10 - BIOCHEMISTRY
Credits
2
Teaching Hours
30
Teaching Term
28/09/2020 ⇒ 15/01/2021
Attendance required
No
Type of Evaluation
Giudizio Finale
Course Content
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Course program
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Lectureship
Teaching Language
Italian
Course Content
- general and organic chemistry
- atoms and molecules
- states of matter;
- redox and acid-base reactions
- Proteins
- Enzymes
- Vitamins
- Carbohydrates
- Glycolysis
- Gluconeogenesis
- Metabolism of Monosaccharides and Disaccharides
- Pentose Phosphate Pathway and NADPH
-Metabolism of Dietary Lipids
- Lipid Metabolism
- Fatty Acid and Triacylglycerol Metabolism
-Amino Acids and Nitrogen
- Tricarboxylic Acid Cycle
- Insulin and Glucagon
- Oxidative Phosphorylation
- atoms and molecules
- states of matter;
- redox and acid-base reactions
- Proteins
- Enzymes
- Vitamins
- Carbohydrates
- Glycolysis
- Gluconeogenesis
- Metabolism of Monosaccharides and Disaccharides
- Pentose Phosphate Pathway and NADPH
-Metabolism of Dietary Lipids
- Lipid Metabolism
- Fatty Acid and Triacylglycerol Metabolism
-Amino Acids and Nitrogen
- Tricarboxylic Acid Cycle
- Insulin and Glucagon
- Oxidative Phosphorylation
Suggested readings (Search our library's catalogue)
1-Stefani, Taddei "Chimica, biochimica e biologia applicata" Zanichelli ed.
2-Bertoldi, Colombo, Magni, Marin, Palestini "Chimica e Biochimica" EdiSES ed.
3-Samaja, Paroni " Chimica e biochimica per le lauree triennali dell'area biomedica" PICCIN ed.
4- Vincenzo N. Talesa Rita Roberti Cinzia Antognelli "Biochimica e biologia per le professioni sanitarie" McGraw-Hill Education Ed.
2-Bertoldi, Colombo, Magni, Marin, Palestini "Chimica e Biochimica" EdiSES ed.
3-Samaja, Paroni " Chimica e biochimica per le lauree triennali dell'area biomedica" PICCIN ed.
4- Vincenzo N. Talesa Rita Roberti Cinzia Antognelli "Biochimica e biologia per le professioni sanitarie" McGraw-Hill Education Ed.
Learning Objectives
This course explores the fundamentals of chemistry and biochemistry and focuses on molecules, solutions, reactions, principles of structure and function of macromolecules and the chemical transformations within the cells of living organisms.
Teaching Methods
Lectures
Type of Assessment
Written examinations of chemistry and biochemistry
Course program
General and organic chemistry:
1. Introduction to the course; units of measurements.
2. Atoms; quantum numbers; atomic orbitals; Aufbau principle; periodic table of the elements; metals; non-metals; semi-metals; periodic properties;
3. Bonds; covalent bonds; homopolar bonds; heteropolar bonds; ionic bonds; octet rule; VSEPR model; formal charge; oxidation number; chemical nomenclature;
4. Chemical reactions; redox reactions; balancing chemical reactions; Lavoisier law; molar mass; moles and Avogadro number.
5. States of matter; state transitions; phase diagrams; solid state; liquid state; gas state and ideal gas law;
6. Solutions and solvation; measurements of concentration; hosmosis and hosmotic pressure;
7. Thermodynamics; first principle; enthalpy; second principle; entropy; Gibbs free energy; spontaneous processes; kinetics; Arrhenius equation; catalysis; equilibrium constants.
8. Acid-base theories; Arrhenius theory; Bronsted theory; Self-ionization of water; pH and pOH; strong and weak bases and acids; buffer solutions.
9. Organic chemistry; synthesis of urea; conventional rules for writing organic chemistry structures; isomers; functional groups; hydrolysis; condensation.
Biochemistry
- Amino Acids
- Protein Structure and Function
- Enzymes
- Vitamins
- Introduction to Carbohydrates
- Glycolysis
- Gluconeogenesis
- Metabolism of Monosaccharides and Disaccharides
- Pentose Phosphate Pathway and NADPH
-Metabolism of Dietary Lipids
- Lipid Metabolism
- Fatty Acid and Triacylglycerol Metabolism
- Nitrogen Metabolism
-Amino Acids Disposal of Nitrogen
- Tricarboxylic Acid Cycle
- Metabolic Effects of Insulin and Glucagon
- Bioenergetics and Oxidative Phosphorylation
1. Introduction to the course; units of measurements.
2. Atoms; quantum numbers; atomic orbitals; Aufbau principle; periodic table of the elements; metals; non-metals; semi-metals; periodic properties;
3. Bonds; covalent bonds; homopolar bonds; heteropolar bonds; ionic bonds; octet rule; VSEPR model; formal charge; oxidation number; chemical nomenclature;
4. Chemical reactions; redox reactions; balancing chemical reactions; Lavoisier law; molar mass; moles and Avogadro number.
5. States of matter; state transitions; phase diagrams; solid state; liquid state; gas state and ideal gas law;
6. Solutions and solvation; measurements of concentration; hosmosis and hosmotic pressure;
7. Thermodynamics; first principle; enthalpy; second principle; entropy; Gibbs free energy; spontaneous processes; kinetics; Arrhenius equation; catalysis; equilibrium constants.
8. Acid-base theories; Arrhenius theory; Bronsted theory; Self-ionization of water; pH and pOH; strong and weak bases and acids; buffer solutions.
9. Organic chemistry; synthesis of urea; conventional rules for writing organic chemistry structures; isomers; functional groups; hydrolysis; condensation.
Biochemistry
- Amino Acids
- Protein Structure and Function
- Enzymes
- Vitamins
- Introduction to Carbohydrates
- Glycolysis
- Gluconeogenesis
- Metabolism of Monosaccharides and Disaccharides
- Pentose Phosphate Pathway and NADPH
-Metabolism of Dietary Lipids
- Lipid Metabolism
- Fatty Acid and Triacylglycerol Metabolism
- Nitrogen Metabolism
-Amino Acids Disposal of Nitrogen
- Tricarboxylic Acid Cycle
- Metabolic Effects of Insulin and Glucagon
- Bioenergetics and Oxidative Phosphorylation